The first head-to-head study
In 32 rats with repaired Achilles tendons, TB-500 significantly raised load to failure, but combining it with BPC-157 added no benefit over either peptide alone.
Joint Diseases and Related Surgery, 2026
In stockBPC-157 + TB-500
A research blend combining BPC-157 and TB-500, two peptides commonly investigated in tissue and cellular research. Each batch is independently tested to verify identity, composition, and purity. For laboratory research use only.
99.62% purity · HPLC Lot TC-076-JZ White Lyophilized Powder
$69.99 $69.99 per 10MG vial
Size: 10MG
- Third-party tested · COA for this lot
- Ships same day when ordered before 3 PM ET
- Free shipping on orders over $49.99
- Questions? Contact support — 860-681-6522
For laboratory research use only. Not for human or animal consumption.
Overview
About BPC-157 + TB-500
This BPC-157 + TB-500 blend pairs two peptides with separate research histories. BPC-157 is a 15-amino-acid chain derived from a protein in gastric juice, studied mostly in vascular and nitric-oxide models. Thymosin beta-4 is a 43-amino-acid protein that binds G-actin, the monomer cells use to build and reshape their internal scaffolding, which is why it's central to cell-migration research. Labs combine them to cover blood-vessel signaling and cell movement in one preparation.
The trouble is the word "TB-500." In 2012, Drug Testing and Analysis identified the acetylated 17–23 fragment of thymosin beta-4, Ac-LKKTETQ, in a product sold as TB-500. That fragment weighs under 900 Da; the full protein weighs more than five times as much. Even a 2026 analysis of independent test reports had to track TB-500 and thymosin beta-4 as separate compounds. Titan Core's blend uses full-length thymosin beta-4, and an independent lab runs every batch through mass spectrometry as well as HPLC, so a fragment can't pass as the real protein. It's made in the USA, and the downloadable report carries the same LOT number as your vial. For laboratory research only; not for human or animal use.
Research highlights
What the literature reports
BPC-157 in human arteries
In internal mammary artery rings from 12 bypass patients, BPC-157 relaxed vessels more with endothelium intact, and blocking nitric oxide synthase blunted it.
Journal of Clinical Medicine, 2026
BPC-157 in limb ischemia
In rats with hind-limb ischemia-reperfusion, BPC-157 lowered malondialdehyde, restored superoxide dismutase and partly restored VEGF.
Scientific Reports, 2026
Tracing BPC-157 metabolism
Isotope-labeled BPC-157 revealed nine metabolites, and the resulting urine method detected it at 0.01–0.11 ng/mL.
Molecules, 2023
Thymosin beta-4 and axon repair
In zebrafish, knocking out TB4 impaired Mauthner axon regeneration and overexpressing it helped, working through G-actin binding.
BMC Biology, 2024
Thymosin beta-4 in colitis models
Oral recombinant TB4 reduced epithelial injury and collagen I deposition in mouse colitis and suppressed mineralocorticoid-receptor signaling.
Molecular Biomedicine, 2026
An iron-binding role
TB4 carries four iron-binding regions and blocked erastin- and glutamate-induced ferroptosis in macrophages.
International Journal of Molecular Sciences, 2022
Specifications
Product details
- Form
- Lyophilized powder (2-peptide blend)
- Purity
- ≥99% (HPLC verified)
- Molecular formula
- BPC-157: C₆₂H₉₈N₁₆O₂₂ · TB-500 (TB4): C₂₁₂H₃₅₀N₅₆O₇₈S
- Molecular weight
- BPC-157: 1419.5 g/mol · TB-500 (TB4): 4963.4 g/mol
- CAS number
- BPC-157: 137525-51-0 · TB-500 (TB4): 77591-33-4
- Presentation
- 10mg · 20mg
- Lot
- TC-076-JZ
- Storage
- Store lyophilized at –20°C, protected from light and moisture.
At a glance
- Third-Party Tested - (COA) Available
- Free 2-Day Shipping on Orders $49.99
- Two Mechanisms, One Fixed Ratio
FAQ
Frequently asked questions
A freeze-dried research blend of BPC-157 and full-length thymosin beta-4 in one vial, so both peptides share a single LOT and ratio.
They're paired to cover vessel and nitric-oxide signaling from BPC-157 and actin-driven cell migration from TB4. Direct evidence on the pairing is still early; see the 2026 tendon study above.
Not always. Some products labeled TB-500 hold only the seven-residue fragment. Titan Core's is the complete 43-residue protein, and its mass on the report shows it.
It's a community nickname borrowed from the fast-healing comic character. It describes how often the two appear together in repair research, not a proven result.
Match the report's LOT to your vial, then check the TB4 mass: it should sit near the full protein's weight in Product Details, far above the fragment. If the LOTs differ, contact support first.
Neither peptide is approved for human use, so no safety profile exists for people, and Titan Core doesn't advise on bpc 157 tb 500 side effects or dosing. It's sold strictly for lab research.
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